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Irritable Bowel Syndrome

2019:  Many Patients With Irritable Bowel Syndrome Have Atypical Food Allergies Not Associated With Immunoglobulin E.
70% of participants were shown to have food reactions and of these, 60.5% reacted to wheat, 20% to yeast, 9.2% to milk, 6.6% to soy, and 4% to egg white.  (9 participants reacted to two of the foods). 
​The authors also state "We therefore hypothesize that our IBS patients have a form of non–IgE-mediated atypical food allergy involving enhanced eosinophil and intraepithelial lymphocyte activation."
2014:  Confocal Endomicroscopy Reveals Food-Associated Changes in the Intestinal Mucosa of Patients with Irritable Bowel Syndrome
In this study, damage to the mucosa could be directly visualized as a result of exposure to the 4 commonly-allergenic foods that were studied.  These people had "Irritable Bowel Syndrome", not Celiac, and 13 of 22 reacted to wheat, 9 of 22 reacted to milk, 6 to yeast and 4 to soy. ​
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