are several blood tests for Celiac Disease, so the first thing to
know is which one(s) you had! If you don't have your actual lab
results, you can ask for a copy from your doctor's office. You may
need to fill out a request form due to the privacy laws, but asking
for a copy of the test is fine - people do it all the time.
you read any journal articles about medical tests, they will refer
to the sensitivity and specificity of the tests. What does this
mean? These terms are a measure of the "trueness" of the
test. Sensitivity is the chance that a person who really does have
an illness, really will have a positive test. Specificity is the
chance that a person who does not have an illness
will have a negative test. In evaluating a test, you would want
the sensitivity and specificity to be as close to 100% as possible.
antibody IgA (AGA-IgA), Antigliadin antibody IgG (AGA-IgG)
Positive antigliadin antibodies mean that the body is reacting
against gliadin, one of the gluten proteins in wheat. A large percentage
of the population has antibodies against gliadin, and many are apparently
healthy, so the interpretation of this test has been very confusing.
fact, these tests are no longer recommended as a screening tool
for CD...and yet they are still run. A positive antigliadin antibody,
with a negative tTG test and biopsy, can cause a lot of concern
when it appears in family members. What does this type of test result
mean - if anything? A study has been published that follows people
who had only antigliadin antibodies.
A new test with good performance. This measures a reaction
to the broken-down gluten molecule (peptide). These peptides are
an integral part of the reaction to gluten in Celiac Disease and
this test is showing good results in diagnosis.
Transglutaminase antibody IgA
Transglutaminase antibody IgG
blood tests / negative biopsy